The above video gives us a little insight that Intelligence seems to be a primary stat in the much-anticipated crafting system in Fallout 4. A little extra brainpower can mean a lot of extra firepower, it seems.
Additionally, the video teases other Intelligence-centric perks like machinery operation, hacking, medical/healing abilities, and alchemy. We haven’t heard much about alchemy’s “chemical compounds” yet, but it’s safe to assume that many compounds will give temporary boosts in other stats and (probably) some will do some exploding. Get smart!